Publications

Research publications written by our team.

Publication Links:

MyNCBI: https://www.ncbi.nlm.nih.gov/myncbi/david.julius.1/bibliography/public/

ORCID ID: https://orcid.org/0000-0002-6365-4867

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels.

Nature neuroscience

Bautista DM, Sigal YM, Milstein AD, Garrison JL, Zorn JA, Tsuruda PR, Nicoll RA, Julius D

A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating.

Neuron

Myers BR, Bohlen CJ, Julius D

Fire in the hole: pore dilation of the capsaicin receptor TRPV1.

Nature neuroscience

Bautista D, Julius D

TRPA1 mediates formalin-induced pain.

Proceedings of the National Academy of Sciences of the United States of America

McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, Fanger CM

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.

Proceedings of the National Academy of Sciences of the United States of America

Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P

TRP channel structural biology: new roles for an old fold.

Neuron

Myers BR, Julius D

The menthol receptor TRPM8 is the principal detector of environmental cold.

Nature

Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D

Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A-/-, 5-HT1B-/-, 5-HT2A-/-, 5-HT3A-/- and 5-HTT-/- knock-out male mice.

Pain

Kayser V, Elfassi IE, Aubel B, Melfort M, Julius D, Gingrich JA, Hamon M, Bourgoin S

TRP channel activation by reversible covalent modification.

Proceedings of the National Academy of Sciences of the United States of America

Hinman A, Chuang HH, Bautista DM, Julius D

The P2Y12 receptor regulates microglial activation by extracellular nucleotides.

Nature neuroscience

Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D