Eric Figueroa, PhD

IRACDA Scholar

Postdoctoral Scholar

[email protected]

Publications

A Cellular Basis for Heightened Gut Sensitivity in Females.

bioRxiv : the preprint server for biology

Venkataraman A, Figueroa EE, Castro J, Navarro FMC, Soota D, Brierley SM, Julius D, Ingraham HA

Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase.

Nature communications

Feng S, Puchades C, Ko J, Wu H, Chen Y, Figueroa EE, Gu S, Han TW, Ho B, Cheng T, Li J, Shoichet B, Jan YN, Cheng Y, Jan LY

A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC).

Channels (Austin, Tex.)

Figueroa EE, Denton JS

Identification of a conserved drug binding pocket in TMEM16 proteins.

Research square

Cheng Y, Feng S, Puchades C, Ko J, Figueroa E, Chen Y, Wu H, Gu S, Han T, Li J, Ho B, Shoichet B, Jan YN, Jan L

Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism.

American journal of physiology. Cell physiology

Figueroa EE, Denton JS

LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology.

American journal of physiology. Cell physiology

Yamada T, Figueroa EE, Denton JS, Strange K

The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel.

Physiological reports

Afzal A, Figueroa EE, Kharade SV, Bittman K, Matlock BK, Flaherty DK, Denton JS

CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor.

American journal of physiology. Cell physiology

Figueroa EE, Kramer M, Strange K, Denton JS

Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992.

Molecular pharmacology

Kharade SV, Kurata H, Bender AM, Blobaum AL, Figueroa EE, Duran A, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, Denton JS

Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590.

Molecular pharmacology

Kharade SV, Sheehan JH, Figueroa EE, Meiler J, Denton JS

ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.

ACS chemical neuroscience

Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS